PEGylation
CHEMICAL REACTION
Pegylated; Pegylation; Pegylate; PEG label; PEG labeling; Peg labeling; Peg label; Peo labeling; Peo label; PEGylated
PEGylation (or pegylation) is the process of both covalent and non-covalent attachment or amalgamation of polyethylene glycol (PEG, in pharmacy called macrogol) polymer chains to molecules and macrostructures, such as a drug, therapeutic protein or vesicle, which is then described as PEGylated. PEGylation affects the resulting derivatives or aggregates interactions, which typically slows down their coalescence and degradation as well as elimination in vivo.